COVID-19 Mutation Tests

COVID-19 Mutation Tests

The SARS-CoV-2 has mutated over time. Most mutations have little effect on the SARS-CoV-2 properties. However, some changes may affect the virus’s properties, such as transmissibility, clinical presentation, and severity of COVID-19.

The World Health Organization (WHO) routinely assesses whether extraordinary events are potentially related with SARS-CoV2. SARS-CoV2 variants that have mutations that change the virus’s infection rate, disease strength and immune system response are termed Variant of Interest – VOI. Among the VOIs that are monitored closely in terms of their global spread and effects, those that pose a global threat are moved from the VOI list to the Variant of Concern – VOC list, thus warning countries about the danger that is approaching. 5 different “Variant of Concern (VOC)” and 2 different “Variant of Interest (VOI)” are identified by WHO as Nov 30, 2021 (https://www.who.int/en/activities/tracking-SARS-CoV-2-variants/).

In routine SARS-CoV-2 screening, alongside the detection of all variants, it is critical to test and distinguish the variants containing mutation. The detection of these variants in regions they are prevalent will decrease the load of variant detection with DNA sequencing. In this regard, upon completion of RT-qPCR for routine SARS-CoV-2 screening, it is critical that the test does not only infer SARS-CoV-2 positivity but also the presence of the variants and mutations.

Bio-Speedy® SARS-CoV-2 mutation kits used for the in vitro qualitative detection of RNA from the epidemic virus SARS-CoV-2 and SARS-CoV-2 variants in different human samples including nasopharyngeal swab (NPS), oropharyngeal swab (OPS), bronchoalveolar lavage (BAL), nasopharyngeal aspirate (NPA), sputum, saliva, and gargle samples from patients suspected of COVID-19 by a healthcare provider or for screening of individuals without symptoms or other reasons to suspect COVID-19.

The Bio-Speedy® SARS-CoV-2 mutation kits test and distinguish SARS-CoV-2 and SARS-CoV-2 variants in a single multiplex RT-qPCR reaction in less than 30 minutes.

COVID-19 Mutation Tests